Rasha Nour ?Eldin Mohamed Essa, Marwa Abd-Alwahab Alkassby, Nahed Samy Khamis And Amr Amin Ghanem,

ABSTRACT


Purpose: To Assess Bone Healing Following Application Of Platelet-rich Fibrin (L-PRF) Versus Xenograft As A Socket Augmentation Material, Using Histological Analysis. Methodology: This Study Was Conducted On 15 Patients (12 Females And 3 Males) With 28 Fresh Extraction Sockets In The Esthetic Zone, With Age Greater Than 18 Years, With A Mean Age (37,5�5) (9 First Premolars, 6 Second Premolars, 4 Canines, 5 Lateral Incisors And 4 Central Incisors). The Patients Were Randomly Allocated To One Of The Four Subgroups According To Time Of Implant Placement: Group A3: (n=7), Group A6 (n=7), Where L-PRF Was Applied Alone Immediately After Extraction. Group B3 (n=7), Group B6 (n=7): In Which Bio-Oss Was Placed Immediately After Extraction. Core Biopsies Where Collected After Either Three Or Six Months And Histomorphometrically Assessed To Calculate Newly Formed Bone And Osteoid Percentages With Regard To Time Of Socket Healing.

Results: There Is Statistical Significant Difference Between The Two Groups Regarding Percentage Of Newly Formed Bone (P<0.05), While There Is No Statistical Significant Difference Regarding Osteoid Percentage Between The Two Groups (P>0.05). Conclusion: Xenograft Remains The Gold Standard In Enhancement Of Bone Remodeling In Post-extraction Socket As Compared To PRF. PRF In The Amount Used In The Current Study Had A Negligible Impact On The Overall Bone Quality Or Quantity In Post-extraction Sockets.